Helena H Ritchie
MS, PhD

Associate Professor of Dentistry

DEPARTMENT

Cariology, Restorative Sciences & Endodontics

ADDRESS

Cariology,Res Sci & Endo
2303 DENT
Ann Arbor MI 48109-1078

CONTACT

734-763-3746

LINKS

BIOGRAPHY

Dr. Ritchie is focused on studying two major dentin noncollagenous proteins -- dentin sialoprotein (DSP) and physophporyn (PP) -- whose appearance is coupled to the conversion of uncalcified predentin to calcified dentin.  The work encompassess following four DSP-PP related areas: (1) regulation and function of rat dentin sialoprotein and phosphophoryn, (2) tissue engineering to test whether DSP and PP proteins can serve as biomimetic molecules in promoting dentin regeneration, (3) DSP-PP gene expression in non-mineralized tissues such as bone, kidney and salivary glands during organogenesis, and (4) DSP-PP precursor processing studies.