Image Shin Lab Our lab advances regenerative medicine by studying how cells build and remodel their microenvironments in health and disease. Using biomaterial engineering, microtechnology, and physical biology, we design cellular niches, direct donor cells and host tissue responses, and investigate extracellular vesicles to promote repair and regeneration. Our work focuses on bone marrow, bone, craniofacial tissues, vasculature, and lungs, with the goal of translating these insights into therapies that restore tissue function and improve patient outcomes.
Image Sasaki Lab The goal of the Sasaki Lab is to develop novel therapeutic approaches for the prevention and treatment of inflammation-associated diseases and to provide better environment for wound healing and tissue regeneration.
Image Ma Lab The Ma laboratory is focused on tissue engineering and regenerative medicine of bone and periodontal tissues: (1) stem cells (embryonic and mesenchymal stem cells) and their interactions with biomaterials; (2) spatially and temporally controlled delivery of growth/differentiation factors using nanotechnologies to mediate cell proliferation and differentiation.
Image Kohn Lab Dr. Kohn’s laboratory focuses on biomineralization, which is investigated by establishing structure-function relations in mineralized tissues, and utilizing this information to develop biomimetic strategies to engineer tissue.
Image Kaigler Lab The Kaigler laboratory is focused on developing novel and innovative approaches for tissue engineering of bone, gingiva, salivary gland tissue, and tooth-related structures (enamel, dentin, dental pulp). Fundamental studies conducted on the molecular level are as aimed at providing rationale and guidance to human studies exploring clinical application.
Image Decker Lab (Joseph) The Decker Lab is focused on developing technologies that 1) detect and interpret the inter- and intra-cellular signaling networks within the tissue microenvironment, 2) alter an existing unfavorable microenvironment and 3) leverage alterations in the pathophysiological microenvironment for early detection and intervention. We have several active research aims towards these goals.
Image Castilho Lab Our laboratory focus on the understanding of the “histone code” in the context of tissue injury, chronic inflammatory diseases, and cancer biology.