Image Graham Rex Holland, BSc, BDS, PhD Professor Emeritus of Dentistry rholland@umich.edu Links Complete CV Biography Dr. Holland maintains a strong interest in pain mechanisms in the tooth and most especially the role of the immune system in producing opoid peptides peripherally. Research in this direction will lead not only to a better understanding of nociception but to new methods of pain control. Dr. Holland is involved in biometrics, evidence-based dentistry, and ethics research.