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Periodontics and Oral Medicine

McCauley Lab - Publications

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McCauley LK, Rosol TJ, Capen CC, Horton JE. A comparison of bone turnover in athymic (nude) and euthymic mice. Biochemical, histomorphometric, bone ash and in vitro studies. Bone 10:29-34, 1989. PMID: 2736153

McCauley LK, Rosol TJ, Capen CC, Horton JE, Shanfeld J. Investigations on in vitro bone resorbing activity from athymic (nude) and euthymic mouse splenic lymphocytes. Bone 10:389-394, 1989. PMID: 2513857

McCauley LK, Rosol TJ, Stromberg PC, Capen CC. In vivo and in vitro effects of interleukin-1aand cyclosporin A on bone and lymphoid tissues in mice. Toxicologic Pathology 19:1-10, 1991. PMID: 2047704

Rosol TJ, Merryman JI, McCauley LK, Capen CC. Effects of transforming growth factor aon parathyroid hormone and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro. Domestic Animal Endocrinology 8:499-507, 1991. PMID: 1786699

McCauley LK, Rosol TJ, Merryman JI, Capen CC. Parathyroid hormone-related protein binding to human T cell lymphotropic virus type I-infected lymphocytes. Endocrinology 130:300-306, 1992. PMID: 1309334

McCauley LK, Rosol TJ, Capen CC. Effects of cyclosporin A on rat osteoblasts (ROS 17/2.8 cells) in vitro. Calcified Tissue International 51:291-297, 1992. PMID: 1330239

Rosol TJ, Merryman JI, McCauley LK, Werkmeister J, Steinmeyer C, Swayne D, Capen CC. Studies on chicken polyclonal antipeptide antibodies specific for parathyroid hormone-related protein (1-36). Veterinary Immunology and Immunopathology 35:321-337, 1993. PMID: 8430499

Nohutcu RM, McCauley LK, Horton JE, Capen CC, Rosol TJ. Effects of hormones and cytokines on stimulation of adenylate cyclase and intracellular calcium concentration in human and canine periodontal ligament cells. Archives of Oral Biology 38:871-879, 1993. PMID: 7506523

Merryman JI, Rosol TJ, McCauley LK, Werkmeister JR, Suter MM, Capen CC. Regulation of parathyroid hormone-related protein production by a squamous carcinoma cell line in vitro. Laboratory Investigation  69: 347-354, 1993. PMID: 8377475

Werkmeister JR, Rosol TJ, McCauley LK, Merryman JI, Horton JE, Capen CC.  Parathyroid hormone-related protein production by normal human keratinocytes in vitro is associated with a less differentiated phenotype.  Experimental Cell Research 208:68-74, 1993. PMID: 8359229

McCauley LK, Beecher CA, Melton ME, Werkmeister JR, Jüppner H, Abou-Samra AB, Segre GV, Rosol TJ.  Transforming growth factor-ß regulates steady state PTH/PTHrP receptor mRNA levels and PTHrP binding in ROS 17/2.8 osteosarcoma cells.Molecular and Cellular Endocrinology  101: 331-336, 1994.  PMID: 9397968

Okada H, Schanbacher FL, McCauley LK, Capen CC, Weckmann M, Rosol TJ. Secretion of parathyroid hormone-related protein by bovine mammary cells in vitro.Journal of Bone and Mineral Metabolism 12:S161-164, 1994.

Rosol TJ, Steinmeyer C, McCauley LK, Grone A, Capen CC, DeWille J. Nucleotide sequences of cDNAs for canine parathyroid hormone-related protein and parathyroid hormone.  Gene 60:241-243, 1995. PMID: 7642102

Nohutcu RM, Somerman MJ, and McCauley LK. Dexamethasone enhances the effects of parathyroid hormone (PTH) on human periodontal ligament (PDL) cells in vitro. Calcified Tissue International 56:571-577, 1995. PMID: 7648489

McCauley LK, Koh AJ, Beecher CA, Cui Y, Decker J, Franceschi RT. Effects of differentiation and transforming growth factor bon PTH/PTHrP Receptor mRNA Levels in MC3T3-E1 Cells. Journal of Bone and Mineral Research 10:1243-1255, 1995. PMID: 8585429

McCauley LK,Koh AJ, Beecher CA, Cui Y, Rosol TJ, Franceschi RT. The PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis. Journal of Cellular Biochemistry 61:638-647, 1996. PMID: 8806088

Fang J, Zhu YY, Smiley E, Bonadio J, Rouleau JA, Goldstein SA, McCauley LK, Davidson B, Roessler B. Stimulation of new bone formation by direct transfer of osteoinductive transgenes. Proceedings of the National Academy of Science ,U.S.A., 93:5753-5758, 1996.  PMID: 8650165

Vander Molen MA, Rubin CT, McLeod KJ, McCauley LK, Donahue HJ. Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks.Journal of Biological Chemistry 271:12165-12171, 1996.  PMID: 8647809

Nohutcu RM, McCauley LK, Somerman MJ. Expression of mineral-associated proteins by periodontal ligament cells: in vitro vs. ex vivo. Journal of Periodontal Research, 31:369-372, 1996. PMID: 8858542

Okada HO, Schanbacher FL, McCauley LK, Weckman MT, Capen CC, Rosol TJ. Bovine mammary cells: A model of PTHrP secretion  in vitro. Domestic Animal Endocrinology , 13:399-410, 1996. PMID: 8886593

Groene A, McCauley LK, Weckman MT, Capen CC, Rosol TJ. Parathyroid hormone/parathyroid hormone-related protein receptor expression in athymic mice with a transplantable canine apocrine adenocarcinoma (CAC-8) and humoral hypercalcemia of malignancy. Journal of Endocrinology, 153:123-129, 1997. PMID: 9135577

Nohutcu RM, McCauley LK, Koh AJ, Somerman MJ. Expression of Extracellular Matrix Proteins in Human Periodontal Ligament Cells During Mineralization In Vitro. Journal of Periodontology, 68:320-327, 1997. PMID: 9150036

McCauley LK, Koh AJ, Beecher CA, Rosol TJ. The proto-oncogene c-fos is transcriptionally regulated by parathyroid hormone and parathyroid hormone related-protein in a cAMP-dependent manner in osteoblastic cells. Endocrinology, 138:5427-5433, 1997.  PMID: 9389528

Donahue HJ, Zhou Z, Li Z,McCauley LK. Age-related decreases in stimulatory G-protein coupled adenylate cyclase in osteoblastic cells. American Journal of Physiology,  273 (4 Pt 1): E776-81, 1997.  PMID: 9357808

Werkmeister JR, Weckman MT, Gröne A, McCauley LK, Wade AB, Blomme E, O’Rourke J, Capen CC, Rosol TJ. Effects of transforming growth factor-b1 on parathyroid hormone-related protein expression by normal human keratinocytes in vitro. Endocrine, 8:291-299, 1998. PMID: 9741834

Wojcik SF, Schanbacher FL, McCauley LK, Zhou H, Kartsogiannis V, Capen CC, Rosol TJ.  Cloning of bovine parathyroid hormone-related protein (PTHrP) cDNA and expression of PTHrP mRNA in the bovine mammary gland. Journal of Molecular Endocrinology, 20:271-280, 1998. PMID: 9584841

Hullinger TG, McCauley LK, DeJoode ML, Somerman MJ. Effect of bone proteins on the metastatic human prostate cancer cell line – DU145 cells in vitro. The Prostate, 36:14-22, 1998. PMID: 9650911

Blomme EAG, Sugimoto Y, McCauley LK, Lin YC, Capen CC, Rosol TJ. Stromal and epithelial cells of the canine prostate express parathyroid hormone-related protein, but not the PTH/PTHrP receptor. The Prostate, 36:110-120, 1998. PMID: 9655263

Anderson DG, Chiego DJ, Glickman GN, McCauley LK. A clinical assessment of the effects of 10% carbamide peroxide gel on human pulp tissue.Journal of Endodontics, 25:247-250, 1999. PMID: 10425949 

Blomme EAG, Dougherty K, Pienta KJ, Capen CC, Rosol TJ, McCauley LK. Skeletal Metastasis of Prostate Adenocarcinoma in Rats: Morphometric Analysis and Role of Parathyroid Hormone-Related Protein. The Prostate, 39:187-197, 1999. PMID: 10334108

Koh AJ, Beecher CA, Rosol TJ, McCauley LK. Cyclic AMP activation in osteoblastic cells: Effects on PTH-1 receptors and osteoblastic differentiation in vitro. Endocrinology, 140:3154-3162, 1999. PMID: 10385409

Dougherty KM, Blomme EAG, Koh AJ, Henderson JE, Pienta KJ, Rosol TJ, McCauley LK. Parathyroid hormone related protein (PTHrP) as a growth regulator of prostate carcinoma. Cancer Research, 59:6015-6022, 1999. PMID: 10606251

Ouyang HJ, McCauley LK, D'Errico JA, Berry JE, Koh-Paige AJ, Strayhorn CL, Somerman MJ. Immortalized murine cementoblasts/periodontal ligament cells respond to parathyroid hormone and parathyroid hormone-related protein stimulation, in vitro. Archives of Oral Biology, 45:293-303, 2000.  PMID:  10708669

Ouyang HJ, McCauley LK, Berry JE, Saygin NE, Tokiyasu Y, Somerman MJ. PTHrP regulates extracellular matrix gene expression in cementoblasts and inhibits cementoblast-mediated mineralization, in vitro. Journal of Bone and Mineral Research, 15:2140-2153, 2000.  PMID: 11092395

Ouyang HJ, Franceschi RT, McCauley LK, Wang D, Somerman MJ. Parathyroid hormone-related protein down regulates bone sialoprotein gene expression in cementoblasts: Role of the protein kinase A pathway. Endocrinology, 141: 4671-4680, 2000. PMID: 11108282

McCauley LK,Koh-Paige AJ, Chen H, Chen C, Ontiveros C, Irwin R, McCabe LR. Parathyroid hormone stimulates fra-2 expression in osteoblastic cells in vitro and in vivo. Endocrinology, 142:1975-1981, 2001. PMID: 11316763

McCauley LK.Transgenic Models of Metabolic Bone Disease. Current Opinion in Rheumatology, 13:316-325, 2001.  PMID: 11555736

Gopalakrishnan R, Ouyang H, Somerman MJ, McCauley LK, Franceschi RT. Matrix Gla Protein is a key regulator of PTH-mediated inhibition of mineralization in osteoblasts. Endocrinology, 142:4379-4388 2001. PMID: 11564701

Keller ET, Zhang J, Cooper CR, Smith PC, McCauley LK, Pienta KJ, Taichman RS. Prostate carcinoma skeletal metastases: Cross-talk between tumor and bone. Cancer Metastasis Reviews, 20:333-349, 2001.  PMID: 12085970

Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK, Use of the Stromal Cell-derived Factor-1/CXCR4 Pathway in Prostate Cancer Metastasis to Bone. Cancer Research 62:1832-1837, 2002. PMID: 11912162

Gröne A, McCauley LK, Capen CC, Rosol TJ. Cloning and Sequencing of the 3’-Region of the Canine Parathyroid Hormone-Related Protein Gene and Analysis of Alternate mRNA Splicing in Two Canine Carcinomas. Domestic Animal Endocrinology, 22(3):169-177, 2002. PMID: 11934525

McCauley LK, Tözüm TF, Rosol TJ. Estrogen Receptors in Skeletal Metabolism: Lessons from Genetically Modified Models of Receptor Function. Critical Reviews in Eukaryotic Gene Expression, 12:89-100, 2002. PMID: 12434924

Chen H, McCauley LK, DeSilva N. Cyclic AMP binding protein assay: an efficient assay for widespread use in cell  signaling studies, Biotechniques, 33:66-72, 2002. PMID: 12139259

Chen H, Demiralp B, Schneider A, Koh AJ, Silve C, Wang C, McCauley LK. Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells. Journal of Biological Chemistry , 277:19374-19381, 2002. PMID: 11897779

Demiralp B, Chen H, Koh AJ, Keller ET,McCauley LK.  Anabolic effects of parathyroid hormone during endochondral bone growth are dependent on c-fosEndocrinology: 143:4038-4047, 2002. PMID: 12239115

McCauley LK, Nohutcu RM.Mediators of Periodontal Osseous Destruction & Remodeling: Principles and Potentials for Therapeutic Intervention. Journal of Periodontology, 73:1377-1391, 2002. PMID: 12479643

Zeng Z, McCauley LK, Wang CY. Hepatocyte Growth Factor Inhibits Anoikis by Induction of AP-1-dependent Cyclooxygenase-2: Implication in Head and Neck Squamous Cell Carcinoma Progression, Journal of Biological Chemistry: 277:50137-50142, 2002. PMID: 12393863

Cooper CR, Chay CH, Gendernalik JD, Lee HL, Bhatia J, Taichman RS, McCauley LK, Keller ET, Pienta KJ. Stromal factors involved in prostate carcinoma metastasis to the bone. Cancer, Feb 1;97 (3 Suppl):739-747, 2003. PMID: 12548571

McCauley LK, Tözüm TF, Kozloff KM, Koh-Paige AJ, Chen C, Demashkieh M, Cronovich H, Richard V, Keller ET, Rosol TJ, Goldstein S. Transgenic Models of Metabolic Bone Disease: Impact of Estrogen Receptor Deficiency on Skeletal Metabolism, Connective Tissue Research , 44:250-263, 2003. PMID: 12952206

Chen H, Frankenberg L, Goldstein S, McCauley LK.  The combination of local and systemic PTH enhances fracture healing. Clinical Orthopedics and Related Research, 416:291-302, 2003. PMID: 14646773

Schneider A, Taboas J, McCauley LK, Krebsbach PK.  Skeletal homeostasis in tissue-engineered bone. Journal of Orthopaedic Research,  21: 859-864,2003. PMID: 12919874

Kalikin LM, Schneider A, Thakur MA, Fridman Y, Griffin LB, Dunn RL, Rosol TJ, Shah RB, Rehemtulla A, McCauley LK, Pienta KJ.  In Vivo Visualization of Metastatic Prostate Cancer and Quantitation of Disease Progression in Immunocompromised Mice. Cancer Biology and Therapeutics. 2:656-660, 2003. PMID: 14588471

Dillon S., Agrawal,A., Van Dyke T., Landreth,G., McCauley LK, Koh A., Maliszewski, C., Akira,S., Pulendran,B. A Toll-Like Receptor 2 Ligand Stimulates Th2 Responses In Vivo, via Induction of Extracellular Signal-Regulated Kinase Mitrogen-Activated Protein Kinase and c-Fos in Dendritic Cells. Journal of Immunology, 4733-4743, 2004. PMID: 15067049

Wei G, Pettway GJ, McCauley LK, Ma PX. The release profiles and bioactivity of parathyroid hormone from poly(lactic-co-glycolic acid) microspheres. Biomaterials.  25(2):345-52, 2004. PMID: 14585722

Dai J, Kitagawa Y, Zhang J, Yao Z, Mizokami A, Cheng S, Nor J, McCauley LK, Taichman RS, Keller ET. Vascular endothelial growth factor contributes to the prostate cancer-induced osteoblast differentiation mediated by bone morphogenetic protein.  Cancer Res. 64(3):994-9, 2004. PMID: 14871830

Tozum TF, Oppenlander M, Koh-Paige AJ, Robins D, McCauley LK. Effects of Sex Steroid Receptor Specificity in the Regulation of Skeletal Metabolism. Calcified Tissue International, 75:60-70, 2004. PMID: 15037970

Boaboid F, Berry JE, Koh AJ, Somerman MJ, McCauley LK. The role of parathyroid hormone related protein (PTHrP) in the regulation of osteoclastogenesis by cementoblasts.  J Periodontol, 75:1247-54, 2004. PMID: 15515341

Loberg RD, Fridman Y, Pienta BA, Keller ET, McCauley LK, Taichman RS, Pienta KJ. Detection and isolation of circulating tumor cells in urologic cancers: A review. Neoplasia: 6:302-309, 2004. PMID: 15256052

Chen C, Koh AJ, Datta NS, Zhang J, Keller ET, Xiao G, Franceschi RT, D’Silva NJ, McCauley LK. Impact of the mitogen-activated protein kinase pathway on parathyroid hormone-related protein actions in osteoblasts. J Biological Chemistry, 279:29121-29129, 2004. PMID: 15128746

Sun YX, Schneider A, Jung JH, Wang J, Dai J, Wang K, Cook K, Ishag-Osman NI, Liang Z, Koh AJ, Shim H, Pienta K, Kleer ET,McCauley LK, Taichman RS. Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.  J Bone Miner Res: 20:318-29, 2005. PMID: 15647826

Datta NS, Chen C, Berry JE,McCauley LK. PTHrP signaling targets cyclin D1 and induces osteoblastic cell growth arrest. J Bone Miner Res Jun;20(6):1051-64, 2005. PMID: 15883646

Lanning SK, Pelok SD, Williams BC, Richards PS, Sarment DP, Oh TJ, McCauley LK. Variation in Periodontal Diagnosis and Treatment Planning Among Clinical Instructors. J. Dental Education 69:325-37, 2005. PMID: 15749943

Schneider A, Kalikin LM, Mattos AC, Keller ET, Allen MJ, Pienta KJ,McCauley LK. Bone turnover mediates preferential localization of prostate cancer in the skeleton.  Endocrinology  146:1727-1736, 2005. PMID: 15637291

Pettway GJ, Schneider A, Koh AJ, Widjaja E, Morris MD, Meganck JA, Goldstein SA, McCauley LK. Anabolic actions of PTH (1-34):  Use of a novel tissue engineering model to investigate temporal effects on bone. Bone 36:959-970, 2005. PMID: 15878317

Koh AJ, Demiralp B, Neiva K, Hooten J., Nohutcu RM, Shim H, Datta NS, Taichman RS, McCauley L.K. Cells of the osteoclast lineage as mediators of the anabolic actions of parathyroid hormone in bone. Endocrinology: 146:4584-4596, 2005. PMID: 16081645

Jung Y, Wang J, Schneider A, Sun YX, Koh AJ, Osman NI,McCauley LK, Taichman RS. Regulation of SDF-1(CXCL12) production by osteoblasts in the hematopoietic microenvironment and a possible mechanism for stem cell homing. Bone: 38:497-508, 2006. PMID: 16337237

Zhang Z, Mitra RS, Henson BS, Datta NS, McCauley LK, Kumar P, Lee JS, Carey TE, D'Silva NJ.  Rap1GAP Inhibits Tumor Growth in Oropharyngeal Squamous Cell Carcinoma. American Journal of Pathology 168:585-596, 2006. PMID: 16436672.

Lanning SK, Best AM, Temple HJ, Richards PS, Carey A, McCauley LK.  Accuracy and consistency of radiographic interpretation among clinical instructors using two viewing systems.  Journal of Dental Education: 70:149-159, 2006.  PMID: 16478929

Berry JE, Ealba E, Pettway GJ, Datta N, Swanson E, Somerman MJ, McCauley LK. JunB as a mediator of the PTHrP actions in cementoblasts. Journal of Bone and Mineral Research: 21:246-257, 2006. PMID: 16418780

Lanning SK, Best AM, Temple HJ, Richards PS, Carey A, McCauley LK. Accuracy and consistency of radiographic interpretation among clinical instructors in conjunction with a training program. Journal of Dental Education 70:545-57, 2006. PMID: 16687640

Padbury AD, Tozum TF, Taba M, Ealba EL, West B, Burney RE, Gauger PG, Giannobile WV, McCauley LK. The impact of primary hyperparathyroidism on the oral cavity. Journal of Clinical Endocrinology and Metabolism 91:3439-3445, 2006. PMID: 16822829

Yamashita J, McCauley LK. The activating protein-1 transcriptional complex: Essential and multifaceted roles in bone.  Clinical Reviews in Bone and Mineral Metabolism 4:107-122, 2006.

Somerman MJ, McCauley LK. Bisphosphonates: sacrificing the jaw to save the skeleton? BoneKEy-Osteovision. IBMS 3(9):12-18, 2006.

Liao J, Schneider A, Datta NS, McCauley LK. Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis.  Cancer Research 66:9065-9073, 2006. PMID: 16982748

Datta NS, Pettway GJ, Chen C, Koh AJ, McCauley LK. Cyclin D1 as a target for the proliferative effects of PTH and PTHrP in early osteoblastic cells.  Journal of Bone and Mineral Research,22:951-64, 2007. PMID: 17501623

Wang H-L, Weber D, McCauley LK.  Effect of Long-term Oral Bisphosphonates on Implant Wound Healing: Literature Review and A Case Report, Journal of Periodontology 78:584-594, 2007. PMID: 17335384

Liao J, McCauley LK. Skeletal metastasis: Established and emerging roles of parathyroid hormone related protein (PTHrP). Cancer Metastasis Rev: 25(4):559-71, 2006. PMID: 17165129

Hou S, McCauley LK, Ma PX.  Synthesis and Erosion Properties of PEG-Containing Polyanhydrides. Macromolecular Bioscience 7:620-628, 2007. PMID: 17457940

Liu X, Pettway GJ, McCauley LK, Ma PX. Pulsatile release of parathyroid hormone from an implantable delivery system. Biomaterials, 28:4124-4131, 2007. PMID: 17576005

Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo SB, Shane E.  Bisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research.  Journal of Bone and Mineral Research 10:1479-1491, 2007. PMID: 17663640

Park BK, Zhang H, Zeng Q, Dai J, Keller E, Giordano T, Gu K, Sha V, Pei, L, Zarbo RJ, McCauley LK. Shi S, Chen, S, Wang, C-Y. NF-κB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF, Nature Medicine, Vol 13 (1):62-69, 2007. PMID: 17159986

Yamashita J, Datta NS, Chun YP, Yang DY, Carey AA, Kreider JM, Goldstein SA, McCauley LK. Role of Bcl2 in osteoclastogenesis and PTH anabolic actions in bone. Journal of Bone and Mineral Research  23(5):621-32, 2008. PMID: 18086008.

Havens AM, Pederson EA, Shiozawa Y, Ying C, Jung Y, Sun Y, Neeley C, Wang J, Mehra R, Keller ET, McCauley LK, Loberg RD, Pienta KJ, Taichman RS. An In Vivo Mouse Model for Human Prostate Cancer Metastasis. Neoplasia, 10:371-380, 2008 PMID: 18392141

Pettway GJ,  Meganck JA, Koh AJ, Keller ET, Goldstein SA, McCauley LK.  Parathyroid Hormone Mediates Bone Growth through the Regulation of Osteoblast Proliferation and Differentiation. Bone, 42:806-18, 2008. PMID: 18234576

Jung Y, Song J, Shiozawa Y, Wang J, Wang Z, Williams B, Havens A, Schneider A, McCauley LK, Krebsbach PH, Taichman RS.   Hematopoietic Stem Cells Regulate Development of Their Niche. Stem Cells: 26:2042-2051, 2008. PMID: 18499897

Liao J, Li X, Koh AJ, Berry JE, Thuda N, Rosol TJ, Pienta KJ, McCauley LK.  PTHrP enhances prostate cancer tumorigenesis, angiogenesis and osteoblastic lesions.  International Journal of Cancer  123: 2267-2278, 2008. PMID: 18729185

Berry JE, Pettway GJ, Cordell K, Jin T, Datta NS, McCauley LK.  JunB as a mediator of PTHrP actions:  New gene targets Ephrin B1 and VCAM-1. Oral Diseases, 14:713-726, 2008. PMID: 18765930   *This paper was selected as “Best Original Article of 2008” in Oral Diseases.

Novince C, Ward B, McCauley LK.  Osteonecrosis of the Jaw: An update and review of recommendations. Cells, Tissues, Organs: 189(1-4):275-83, 2009. PMID: 18765930

Li X, Loberg R, Liao J, Ying C, Snyder L, Pienta KJ, McCauley LK. A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone. Cancer Research, 69:1685-92, 2009.  PMID: 19176388

Chang J, Wang Z, Tang E, Fan Z, McCauley LK, Franceschi R, Guan K, Krebsbach PH, Wang CY. Inhibition of osteoblast functions by IKK/NF-kB in osteoporosis. Nature Medicine: 15:682-9, 2009. PMID: 19448637

Toribio RE,  Brown H,  Novince C, Marlow B, Hernan K, Lanigan L, Hildreth B, Werbeck J, Shu S, Lorch G, Carlton M, Foley J, Bokaya B,   McCauley LK, Rosol TJ. The mid-region, nuclear localization sequence and C-terminus of PTHrP regulate skeletal development, hematopoiesis and survival in mice. FASEB Journal, 24:1947-57, 2010. PMID: 20145205

Wang Z, McCauley LK. Osteoclasts and odontoclasts: signaling pathways to development and disease. Oral Diseases: 17:129-142, 2011, PMID: 20659257.

Thudi NK, Martin CK, Murahari S, Shu SS, Lanigan LG, Werbeck JL, Keller ET, McCauley LK, Pinzones JJ, Rosol TJ. Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases.  Prostate: On-Line October, 2010, PMID: 20957670

Yamashita J, McCauley LK, Van Poznak C.  Updates on Osteonecrosis of the Jaw. Current Opinion in Supportive & Palliative Care: 4(3):200-6,2010, PMID: 20657284.

Yamashita J, Yang DY, Koi A,  McCauley LK.  Effect of zoledronic acid on bone marrow and oral wound healing in rats.  Clinical Cancer Research, 17:1405-1414,2011, PMID: 21149614.

Bagramian RA, Taichman RS, McCauley LK, Green TG, Inglehart MR. Mentoring of dental and dental hygiene faculty: A case study. Journal of Dental Education: In press, 2011.

Pirih F, Michalski M, Koh A, Berry J, Ghaname E, Kamarajan P, Bonnelye E, Ross C, Kapila Y, Jurdic P, McCauley LK. The impact of parathyroid hormone on cells of the hematopoietic lineage: in vivo and ex vivo studies. PloS One, Oct 27;5(10):e13657,2010, PMID: 21048959.

McCauley LK. C-Maf and you won’t see fat. Journal of Clinical Investigation: 120:3440-2, 2010, PMID: 20877008.

Bashutski JD, Eber R, Kinney J, Benavides E, Maitra S, Braun TM, Giannobile WV, McCauley LK. Teriparatide and osseous regeneration in the oral cavity. New England Journal of Medicine: Vol 363: 2396-2405, 2010, PMID: 20950166.

Li X, Koh AJ, Soki F, Park S, Pienta K, McCauley LK.  Inhibitory effects of megakaryocytes in prostate cancer skeletal metastasis. Journal of Bone and Mineral Research: 26:125-134, 2011 PMID: 20684002.

Thudi NK, Shu ST, Martin CK, Lanigan LG, Nadella MVP, Van Bokhoven A, Werbeck JL, Simmons JK, Murahari S, Kisseberth WC, Breen M, Williams C, Chen C, McCauley LK, Keller ET, Rosol TJ. Development of a brain metastatic canine prostate cancer cell line. Prostate: 71:615-625, 2011.

Li X, Liao J, Park SI, Koh AJ, Sadler WD,Pienta KJ, Rosol TJ, McCauley LK. Drugs Which Inhibit Osteoclast Function Suppress Tumor Growth through Calcium Reduction in Bone. Bone: 48:1354-1361, 2011. PMID: 21419883

Bashutski JD, Eber R, Kinney J, Benavides E, Maitra S, Braun TM, Giannobile WV, McCauley LK. The impact of vitamin D status on periodontal surgery outcomes.  Journal of Dental Research: 09:1007-1012,  2011. PMID: 21555774

Motyl KJ, McCauley LK, McCabe LR. Amelioration of Type I Diabetes-induced Osteoporosis by Parathyroid Hormone is Associated with Improved Osteoblast Survival. Journal of Cellular Physiology: 227:1326-1334,  2012. PMID: 21604269

Weilbaecher KN, Guise TA, McCauley LK.  Cancer to bone: a fatal attraction (Invited review): Nature Reviews Cancer: 11:411-25. PMID: 21593787

Novince CM, Koh AJ, Michalski MN, Marchesan JT, Wang J, Jung Y, Berry JE, Eber MR, Rosol TJ, Taichman RT,   McCauley LK. Proteoglycan-4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells.  American Journal of Pathology: 179:2431-2442, 2011. PMID:21939632.

Koh AJ, Novince CM, Li X, Wang T, Taichman RT, McCauley LK.  An Altered Murine Bone Marrow Microenvironment Impacts Anabolic Actions of PTH. Endocrinology, 152(12):4525-36, 2011. PMID: 22045660

McLean K, Gong Y, Choi Y, Deng N, Yang K, Bai S, Cabreara L, Keller E, McCauley L, Cho K, Buckanovich R. Human Ovarian Carcinoma Associated MSC Regulate Cancer Stem Cells and Tumorigenesis via Altered BMP Production. Journal of Clinical Investigation: 121:3206-3219, 2011. PMID: 21737876

Danciu TE, Li Y, Koh AJ, Xiao G, McCauley LK, Franceschi RT.  The basic helix loop helix transcription factor twist1 is a novel regulator of ATF4 in osteoblasts. Journal of Cellular Biochemistry: 113:70-79, 2012. PMID: 21866569

Novince CM, Michalski MN,  Sinder BP,Entezami P,  Koh AJ, Eber MJ, Pettway GJ,  Rosol TJ,  Wronski TJ,   Kozloff KM, McCauley LK. Proteoglycan-4: a dynamic regulator of skeletogenesis and PTH skeletal anabolism.  Journal of Bone and Mineral Research:  27:11-25, 2012. PMID 21932346. Video Abstract:

Novince CM, Entezami P, Wilson CG, Wang J, Koh AJ, Michalski MN, Sinder BP, Kozloff KM, Taichman RS, Warman ML, McCauley LK. The impact of proteoglycan-4 and parathyroid hormone on articular cartilage degeneration. Journal of Orthopaedic Research: Conditionally accepted, 2012.

Bashutski JD, Kinney J,  Benavides E, Maitra S,  Braun T,  Giannobile WV,  McCauley LK,  Eber RM. Systemic teriparatide administration promotes osseous regeneration of an intrabony defect: A Case Report. Clinical Advances in Periodontics: 2:66-71, 2012.

Park SI, Soki FN, McCauley LK. Roles of bone marrow cells in skeletal metastases: No longer bystanders. Cancer Microenvironment: 4:237-246, 2011. PMID: 21809058

Yu C, Shiozawa Y, Taichman RS, McCauley LK, Pienta KJ, Keller ET. Prostate cancer and parasitism of the bone hematopoietic stem cell niche. Critical Reviews in Eukaryotic Gene Expression: In press, 2012.

Park SI, McCauley LK. Nuclear localization of parathyroid hormone-related peptide confers resistance to anoikis in prostate cancer cells. Endocrine Related Cancer: In press, on-line, 2012. PMID:22291434

Jung Y, Shiozawa Y, Wang J, McGregor N, Dai J, Park SI, Berry JE, Havens AM, Joseph J, Kim JK, Patel L, Carmeliet P, Daignault S, Keller ET, McCauley LK, Pienta KJ, Taichman RS. Prevalence of prostate cancer metastases following intravenous inoculation provides clues into the molecular basis of dormancy in the bone marrow microenvironment. Neoplasia: In press, 2012.

Park SI, Liao J, Berry J, Li X, Koh A, Michalski M, Eber M, Soki F, Sadler W, Sud S, Tisdelle S,  Daignault SD, Nemeth J,  Snyder L, Wronski T, Pienta K, McCauley LK. Cyclophosphamide creates a responsive microenvironment for prostate cancer skeletal metastasis.Cancer Research: In press, 2012.  Press release May 15, 2012

McCauley LK, Martin TJ. Twenty-five years of PTHrP progress from cancer hormone to multifunctional cytokine. Invited Perspective, Journal of Bone and Mineral Research: In press, 2012.PMID:22549910

Soki FN, Park SI, McCauley LK. The multi-faceted actions of parathyroid hormone related protein in skeletal metastasis.  Invited review, Future Oncology: Conditionally accepted, 2012.



McCauley LK and Somerman MJ. Biological modifiers in periodontal regeneration. In: Dental Clinics of North America, Ed: Vandersall DC, Pub: W.B. Saunders, Vol 42 (2):361-387, 1998. PMID: 9597341

McCauley LK,  Schneider A.  PTHrP and Skeletal Metastasis. In: The Biology of Bone Metastases. Editors: Keller ET, Chung LW.  Cancer Treat Res. 118:125-47, 2004. PMID: 15043191

Rosol TJ, Tannehill-Gregg S, Corn S, Schneider A, McCauley LK.  Animal Models of Bone Metastasis. In: The Biology of Bone Metastases. Editors: Keller ET, Chung LW.  Cancer Treat Res. 118:47-81, 2004.  PMID: 15043188

Pettway GJ, McCauley LK, Ossicle and vossicle implant model systems. Methods in Molecular Biology/Molecular Medicine: Osteoporosis: 455:101-10, 2008.

Pirih F, McCauley LK, Wacktawski-Wende J. Oral Manifestations of Metabolic Bone Disease. Chapter 109, 7th Edition, ASBMR Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, p513-517, 2008.

Park S, McCauley LK, Gallick GE. Pre-Clinical Mouse Models of Prostate Cancer, in: Current Protocols  in Pharmacology and Drug Discovery, 51:14.15-14.15.27.,2010. PMID: 21483646

Bashutski J, Taichman S, McCauley LK. Impact of Metabolic Bone Disease on Craniofacial Bones and Teeth, In Mineralized Tissues in Oral and Craniofacial Science: Biological Principles and Clinical Correlates, Edited by McCauley LK and Somerman MJ., Wiley-Blackwell Publishers, ISBN 978-0-470-95833-9, 2012.


Non-Peer-Reviewed Publications

Creath CJ, Hipsher TG, McCauley LK. Review of the activities of the AADS Council of Students. Journal of Dental Education 51:486-488, 1987. PMID: 3475333

Horton JE, McCauley LK. On the loss of alveolar bone in periodontal disease. In Proceedings of "Symposium on Current Topics in Periodontal Disease." Ikedo T, et al (Eds.) Nihon University at Matsudo, Japan. pp. 23-33 (Jap.); 109-121 (Eng.) 1990.

Horton JE, McCauley LK. Mechanisms and control of alveolar bone loss in periodontal disease. In Recent Advances in Periodontology, Volume II.  Gold S, et al, (Eds.), Elsevier, Amsterdam. pp. 23-30, 1991.

Rosol TJ, Merryman JI, McCauley LK, Werkmeister J, Swayne D, Capen CC. Pathogenesis of cancer-associated hypercalcemia of malignancy: characterization of polyclonal antibodies to parathyroid hormone-related protein. Published in Vitamin D -1991: Molecular, Cellular, and Clinical Endocrinology. A. W. Norman, K. Schaefer, H.G. Grigoleit, D. V Herrath, Eds. Walter de Gruyter, Berlin/New York, 1991.

Rosol TJ, McCauley LK, Steinmeyer CL, Capen CC. Nucleotide sequence of canine preproparathyroid hormone. In: The Comparative Endocrinology of Calcium Regulation. Eds: C Dacke, J Danks, I Caple, and G Flik. Bristol, Journal of Endocrinology Ltd., pp201-203, 1996.

Klibanski A, Adams-Campbell L, Bassford T, Blair SN, Boden SD, Glasse L, Gifford D, Goldring S, Dickersin K, Hruska K, Johnson SR, McCauley LK, Russell W. Consensus Development Conference Statement on Osteoporosis Prevention, Diagnosis, and Therapy.  National Institutes of Health, 2000.

Robert L. Vessella, Theresa A. Guise, Edward S. Susman, Larry J. Suva, Gregory A. Clines, Scott L. Kominsky, Kristy L. Weber, John M. Chirgwin, Laurie K. McCauley, and Wende Kozlow Meeting Report from Skeletal Complications of Malignancy IV: A symposium jointly sponsored by The Paget Foundation for Paget's Disease of Bone and Related Disorders, the National Cancer Institute, and the University of Virginia School of Medicine, April, 2005 Bethesda, Maryland, USA
BoneKEy-Osteovision 2006 Mar 1 doi:10.1138/20060203

Schipani E, Ferrari S, Datta NS, McCauley LK, Vignery A, Bellido T, Strewler GJ, Turner CH, Jiang Y, Seeman E. Meeting Report from the 28th Annual Meeting of the American Society for Bone and Mineral Research. BoneKEy-Osteovision. 2006 November;3(11):14-50.

McCauley LK. Bisphosphonate-associated ONJ: at the interface of dentistry and medicine: Invited Commentary. Endocrine Today, October 2007.

Khosla S, Burr D, Cauley J, Dempster DW, Ebeling PR, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo SB, Shane E.   Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg. 2008 Jun;66(6):1320-1 (Letter to the Editor) PMID: 18486811

Novince C, McCauley LK. Toward a better understanding of bisphosphonates and their potential for impacting orthodontic therapy.  Proceedings of the Moyers Symposium, 2008.

Pirih FQ, Zablotsky M, Cordell K, McCauley LK.  Case report of implant placement in a patient with Paget’s disease on bisphosphonate therapy.  Journal of the Michigan Dental Association, 91:38-43, 2009. PMID: 19537656

Park SI, McCauley LK.  IBMS Bone Key Meeting Report “Imaging and Proteomics of Bone Metastasis:  The Ninth International Meeting on Cancer Induced Bone Disease October 28-31, 2009 in Arlington, Virginia, the USA, BoneKEy-Osteovision. 2010 January.

Cho SW, McCauley LK. Parathyroid hormone: A dynamic regulator of bone, immune, and hematopoietic cells. In press, 2012.