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Cariology, Restorative Sciences, and Endodontics

Ritchie Lab

Helen Ritchie Photo


Welcome to the Ritchie Lab

Helena Ritchie, MS, PhD
Associate Professor
helenar@umich.edu

Ritchie Profile


Research Interests

Research scope is focused on dentin sialoprotein (DSP) and phosphophoryn (PP).  Current research areas include DSP-PP gene regulation, DSP-PP precursor protein processing, and DSP/PP functional roles during tissue development.

Recent Publications

  1. Tang XN, Zhu YQ, Marcelo CL, Ritchie HH.  Expression of mineralized tissue associated proteins: Dentin sialoprotein and phosphophoryn in rodent hair follicles. J Dermatological Science Nov; 64(2):92-98, 2011.
  2. Li LF, Zhu YQ, Jiang L, Peng WW, Ritchie HH.  Hypoxia promotes mineralization of human dental pulp cells. J Endod April; 37(6):799-802, 2011.
  3. Jiang L, Zhu Y, Du R, Gu YX, Xia L, Qin F, Ritchie HH. The expression and role of stromal cell-derived factor-1alpha-CXCR4 axis in human dental pulp. J Endod Aug; 34(8):939-944, 2008.
  4. Godovikova V, Ritchie HH.  Dynamic processing of recombinant dentin sialoprotein-phosphophoryn protein. J Biol Chem Oct 26;282(43):31341-31348, 2007.
  5. Liu J, Jin t, Chang S, Ritchie HH, Smith AJ, Clarkson BH. Maxtrix and TGF-beta-related gene expression during human dental pulp stem cell (DPSC) mineralization.  In Vitro Cell Dev Biol Anim Mar-Apr; 43(3-4):120-128, 2007.
  6. Lee YL, Lin FH, Wang WH, Ritchie HH, Lan WH, Lin CP. Effects of EDTA on the hydration mechanism of mineral trioxide aggregate. J Dent Res Jun;86(6):534-538, 2007.
  7. Lee YL, Liu J, Clarkson BH, Lin CP, Godovikova V, Ritchie HH.  Dentin-pulp complex responses to carious lesions. Caries Res 40(3):256-264, 206.
  8. Godovikova V, Li XR, Saunders TL, Ritchie HH.  A rta 8 kb dentin sialoprotein-phosphophoryn (DSP-PP) promoter directs spatial and temporal LacZ activity in mouse tissues.  Dev Biol Jan 15;289(2):507-516, 2006.

 

updated: 03/18/2014